Objectives: To investigate the prevalence of frailty using a Tilburg frailty indicator in older community-dwelling adults referring to the health centers covered by Tehran University of Medical Sciences. Design: In this cross-sectional survey, all adults aged 60 and older living in Tehran were eligible to participate, including older adults with cognitive impairment provided a close relative was able to assent on their behalf. All participants were community dwelling because institutionalization is very rare. Participants were screened using a short frailty screening tool, the Brief Frailty Instrument for Iran, comprising two validated GAD2 and PHQ2 questionnaires to investigate the relationship between vulnerability and anxiety and depression. Based on TFI score, a frailty-weighted, stratified sample was selected for in-depth assessment and characterized as frail or not frail. Results: Out of 1354 completed questionnaires, 60% of the scores were above 5 and therefore were frail. Conclusion: given the high prevalence of this disorder, it is necessary to take effective measures to prevent the spread of this complication in Iranian aging population.